Vaccination with genetically modified Shiga-like toxin IIe prevents edema disease in swine.

@article{Bosworth1996VaccinationWG,
  title={Vaccination with genetically modified Shiga-like toxin IIe prevents edema disease in swine.},
  author={Brad T. Bosworth and James E. Samuel and Harley W. Moon and Alison D. O'Brien and Victor M. Gordon and S. C. Whipp},
  journal={Infection and immunity},
  year={1996},
  volume={64 1},
  pages={55-60}
}
Escherichia coli strains producing Shiga-like toxin II variant (SLT-IIe, formerly called SLT-IIv) cause edema disease in weaned pigs. Vaccination of pigs with a genetically modified form of Shiga-like toxin IIe, SLT-IIe(E167Q), has been previously shown to be nontoxic and to induce antibodies to SLT-IIe (V.M. Gordon. S.C. Whipp, H.W. Moon, A.D. O'Brien, and J.E. Samuel, Infect, Immun. 60:485-502, 1992). Fifty micrograms of SLT-IIe(E167Q) toxin was used to vaccinate suckling pigs at 1 and 2… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…