Vaccination with dendritic cell/tumor fusions following autologous stem cell transplant induces immunologic and clinical responses in multiple myeloma patients.

@article{Rosenblatt2013VaccinationWD,
  title={Vaccination with dendritic cell/tumor fusions following autologous stem cell transplant induces immunologic and clinical responses in multiple myeloma patients.},
  author={Jacalyn M Rosenblatt and Irit Avivi and Baldev Vasir and L William Uhl and Nikhil C. Munshi and Tami Katz and Bimalangshu R. Dey and Poorvi Somaiya and H. Brooker Mills and Federico Campigotto and E. Richard Weller and Robin M. Joyce and James D. Levine and Dimitrios Tzachanis and Paul Richardson and Jacob P Laubach and Noopur Raje and Vassiliki A Boussiotis and Yan Emily Yuan and Lina Bisharat and Viki Held and Jacob M. Rowe and Kenneth J. Anderson and Donald Kufe and David Avigan},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2013},
  volume={19 13},
  pages={
          3640-8
        }
}
PURPOSE A multiple myeloma vaccine has been developed whereby patient-derived tumor cells are fused with autologous dendritic cells, creating a hybridoma that stimulates a broad antitumor response. We report on the results of a phase II trial in which patients underwent vaccination following autologous stem cell transplantation (ASCT) to target minimal residual disease. EXPERIMENTAL DESIGN Twenty-four patients received serial vaccinations with dendritic cell/myeloma fusion cells following… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 66 CITATIONS

The Role of Immunotherapy in Multiple Myeloma

  • Pharmaceuticals
  • 2016
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Harnessing immunosurveillance: current developments and future directions in cancer immunotherapy

  • ImmunoTargets and therapy
  • 2014
VIEW 5 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Interleukin 12: still a promising candidate for tumor immunotherapy?

  • Cancer Immunology, Immunotherapy
  • 2014
VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2007
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

  • Averaged 12 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 29 REFERENCES

Multiple myeloma.

  • The New England journal of medicine
  • 2011

Similar Papers

Loading similar papers…