Vaccination with a soluble recombinant hemagglutinin trimer protects pigs against a challenge with pandemic (H1N1) 2009 influenza virus.

@article{Loeffen2011VaccinationWA,
  title={Vaccination with a soluble recombinant hemagglutinin trimer protects pigs against a challenge with pandemic (H1N1) 2009 influenza virus.},
  author={Willie Loeffen and Robert P. de Vries and Norbert Stockhofe and Diana J. van Zoelen-Bos and R. J. L. M. Maas and Guus Koch and Rob J. M. Moormann and Peter J. M. Rottier and Cornelis A M de Haan},
  journal={Vaccine},
  year={2011},
  volume={29 8},
  pages={
          1545-50
        }
}
In 2009 a new influenza A/H1N1 virus strain ("pandemic (H1N1) 2009", H1N1v) emerged that rapidly spread around the world. The virus is suspected to have originated in swine through reassortment and to have subsequently crossed the species-barrier towards humans. Several cases of reintroduction into pigs have since been reported, which could possibly create a reservoir for human exposure or ultimately become endemic in the pig population with similar clinical disease problems as current swine… CONTINUE READING
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