Vaccination with Staphylococcus aureus fibrinogen binding proteins (FgBPs) reduces colonisation of S. aureus in a mouse mastitis model.

@article{Mamo1994VaccinationWS,
  title={Vaccination with Staphylococcus aureus fibrinogen binding proteins (FgBPs) reduces colonisation of S. aureus in a mouse mastitis model.},
  author={W Mamo and M K Bod{\'e}n and J. I. Flock},
  journal={FEMS immunology and medical microbiology},
  year={1994},
  volume={10 1},
  pages={
          47-53
        }
}
A mouse mastitis model was used to study the effect of vaccination with fibrinogen binding proteins and collagen binding protein from Staphylococcus aureus against challenge infection with S. aureus. The mice vaccinated with fibrinogen binding proteins showed reduced rates of mastitis compared with controls. Gross examination of challenged mammary glands of mice showed that the glands of mice immunized with fibrinogen binding proteins developed mild intramammary infection or had no pathological… CONTINUE READING

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