Vaccination therapy for non-small-cell lung cancer: review of agents in phase III development.

  title={Vaccination therapy for non-small-cell lung cancer: review of agents in phase III development.},
  author={Lynn Decoster and Isabelle Wauters and Johan Vansteenkiste},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  volume={23 6},
The historical results of cancer vaccination for non-small-cell lung cancer (NSCLC) were disappointing. In the current decade, however, new insights in the interaction between tumours and the immune system have led to the development of immunotherapy as a fundamentally new concept for the treatment of NSCLC. Modern NSCLC vaccine strategies rely on better identification of antigenic targets, addition of strong immunoadjuvants, and use of more efficient delivery systems. These treatments have… CONTINUE READING


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