Vaccination strategies for neuro-oncology.

  title={Vaccination strategies for neuro-oncology.},
  author={John H. Sampson and Duane A. Mitchell},
  volume={17 Suppl 7},
Vaccination against cancer-associated antigens has long held the promise of inducting potent antitumor immunity, targeted cytotoxicity while sparing normal tissues, and long-lasting immunologic memory that can provide surveillance against tumor recurrence. Evaluation of vaccination strategies in preclinical brain tumor models has borne out the capacity for the immune system to effectively and safely eradicate established tumors within the central nervous system. Early phase clinical trials have… CONTINUE READING
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