Vaccination of the immunocompromised child

@article{Casswall2005VaccinationOT,
  title={Vaccination of the immunocompromised child},
  author={T. Casswall and B. Fischler},
  journal={Expert Review of Vaccines},
  year={2005},
  volume={4},
  pages={725 - 738}
}
The development of vaccination is a major achievement in modern medicine. However, children treated with immunosuppression may not at all, or only in part, receive routine immunization due to uncertainty of its risks and effect. There is a substantial lack of pediatric studies concerning the efficacy and safety of vaccination in this patient group. Experience from similar adult groups and children with HIV infection can be used as a model for other disease categories. With increasing knowledge… Expand
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The aim of this article is to update paediatricians on vaccination recommendations and relevant reference sources and the use of individual vaccines in children with special vaccination requirements. Expand
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Although randomized controlled trials in transplant recipients have not been performed for most new licensed vaccines, preliminary recommendations can be formulated based on current data and guidelines, and it will be important to determine the indications and optimal timing of newer immunizations and immunization strategies. Expand
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An expanded initiative from the Central European Vaccination Awareness Group aims to raise awareness of the different high-risk paediatric groups, differentiate them according to their specific risk, and formalise a guidance statement for the immunization of each population. Expand
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The article uses four special risk groups (acute lymphoblastic leukemia; preterm birth; juvenile idiopathic arthritis; and inflammatory bowel disease), to highlight the management considerations and potential vaccination strategies. Expand
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Children receiving anti-TNF treatment and vaccinated with PCV7 achieved a significantly lower GMTs against serotypes 4, 14 and 23F, and no patient developed vaccine-associated serious adverse events or disease flares. Expand
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Children with JIA had an adequate response to pneumococcal vaccine and the response was influenced by MTX and prednisone treatment. Expand
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  • Biology, Medicine
  • Drug discovery today
  • 2008
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The development of vaccines against intracellular bacterial pathogens has proven to be more challenging, partly due to the problems associated with the identification of protective antigens and partly with the difficulties associated with inducing CD8(+) T cell responses. Expand
Survivors of childhood cancer: An Australian audit of vaccination status after treatment
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The aim of this study was to describe the compliance of post‐chemotherapy revaccination of childhood cancer survivors relative to current Australian guidelines. Expand
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Rational vaccine design whereby avirulent strains are equipped with the capabilities to induce protection but lack detrimental inflammatory effects offer great promise towards future studies using non-pathogenic bacteria as vectors for vaccination. Expand
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