Vaccination of puppies born to immune dams with a canine adenovirus-based vaccine protects against a canine distemper virus challenge.

@article{Fischer2002VaccinationOP,
  title={Vaccination of puppies born to immune dams with a canine adenovirus-based vaccine protects against a canine distemper virus challenge.},
  author={Laurent Fischer and Jean Phillipe Tronel and Camilla Pardo-David and Patrick A Tanner and Guy Colombet and Jules Maarten Minke and Jean-Christophe F Audonnet},
  journal={Vaccine},
  year={2002},
  volume={20 29-30},
  pages={3485-97}
}
None of the currently available distemper vaccines provides a satisfactory solution for the immunization of very young carnivores in the face of maternal-derived immunity. Since mucosal immunization with replication-competent adenovirus-based vaccines has been proven effective in the face of passive immunity against the vector, it has the potential to provide a solution for the vaccination of young puppies born to canine distemper virus (CDV)-immune dams. We report the engineering and the… CONTINUE READING