Vaccination of horses against strangles using recombinant antigens from Streptococcus equi.

@article{Waller2007VaccinationOH,
  title={Vaccination of horses against strangles using recombinant antigens from Streptococcus equi.},
  author={Andrew Waller and Margareta Flock and Kenneth G C Smith and Carl Peter Robinson and Zoe Mitchell and Asa Karlstr{\"o}m and Jonas Lannerg{\aa}rd and Rune Bergman and Bengt Guss and Jan-Ingmar Flock},
  journal={Vaccine},
  year={2007},
  volume={25 18},
  pages={3629-35}
}
Strangles is an upper respiratory tract infection in horses, which is highly contagious and one of the more costly diseases of the horse. Three recombinant antigens were used to vaccinate horses, which were then experimentally challenged with Streptococcus equi, the causative agent for strangles. The vaccinated horses showed significantly reduced bacterial growth (p=0.02) and nasal discharge (p=0.0004), a typical symptom of strangles. Other clinical signs of strangles were also reduced and at… CONTINUE READING

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