Vaccination of dogs against Babesia canis infection using antigens from culture supernatants with emphasis on clinical babesiosis.

@article{Schetters1994VaccinationOD,
  title={Vaccination of dogs against Babesia canis infection using antigens from culture supernatants with emphasis on clinical babesiosis.},
  author={Theo P. M. Schetters and Jos Kleuskens and Nicolette C Scholtes and Jaco W. Pasman and Harry J. Bos},
  journal={Veterinary parasitology},
  year={1994},
  volume={52 3-4},
  pages={
          219-33
        }
}
Groups of five dogs were vaccinated with Babesia canis antigens from in vitro culture in combination with saponin as adjuvant. Protection against challenge infection was evident as diminished clinical disease, decrease in parasitaemia, and a less marked fall in haematocrit values. Recovery from infection occurred at the time a memory immune response became effective (from Days 5 to 6 after challenge infection onwards). The effect was dose dependent, the highest antigen dose being most effective… CONTINUE READING
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