Vaccination of dendritic cells loaded with interleukin-12-secreting cancer cells augments in vivo antitumor immunity: characteristics of syngeneic and allogeneic antigen-presenting cell cancer hybrid cells.

Abstract

Cancer immunotherapy by fusion of antigen-presenting cells and tumor cells has been shown to induce potent antitumor immunity. In this study, we characterized syngeneic and allogeneic, murine macrophage/dendritic cell (DC)-cancer fusion cells for the antitumor effects. The results showed the superiority of allogeneic cells as fusion partners in both types… (More)

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@article{Suzuki2005VaccinationOD, title={Vaccination of dendritic cells loaded with interleukin-12-secreting cancer cells augments in vivo antitumor immunity: characteristics of syngeneic and allogeneic antigen-presenting cell cancer hybrid cells.}, author={Takuji Suzuki and Tatsuro Fukuhara and Masashi Tanaka and Akira Nakamura and Kenichi Akiyama and Tomohiro Sakakibara and Daizo Koinuma and Toshiaki Kikuchi and Ryushi Tazawa and Makoto Maemondo and Koichi Hagiwara and Yasuo Saijo and Toshihiro Nukiwa}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2005}, volume={11 1}, pages={58-66} }