Vaccination of calves against bovine herpesvirus-1: assessment of the protective value of eight vaccines.

@article{Castrucci2002VaccinationOC,
  title={Vaccination of calves against bovine herpesvirus-1: assessment of the protective value of eight vaccines.},
  author={G. Castrucci and Ferdinando Frigeri and Daniela Salvatori and M Ferrari and Q Sardonini and Enzo Cassai and Dico M Lo and Antonella Rotola and Riccardo Angelini},
  journal={Comparative immunology, microbiology and infectious diseases},
  year={2002},
  volume={25 1},
  pages={29-41}
}
Eight separate, but related experiments, were carried out in which groups of six calves were vaccinated with one of eight commercial vaccines. In each experiment the vaccinated calves were subsequently exposed to three calves infected with virulent bovine herpesvirus-1 (BHV-1). In each experiment, all infected donor calves developed a typical severe infectious bovine rhinotracheitis (IBR) infection and excreted virus in their nasal secretions of up to 10(8.00) TCID50/0.1 ml. One live BHV-1 gE… CONTINUE READING
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