Vaccination of Manchego lambs against Haemonchus contortus with a somatic fraction (p26/23) of adult parasites.

@article{DomnguezTorao2000VaccinationOM,
  title={Vaccination of Manchego lambs against Haemonchus contortus with a somatic fraction (p26/23) of adult parasites.},
  author={I A Dom{\'i}nguez-Tora{\~n}o and Montserrat Cuquerella and Ma T G{\'o}mez-Mu{\~n}oz and Susana Barbosa M{\'e}ndez and Francisco Jos{\'e} Fern{\'a}ndez-P{\'e}rez and Jos{\'e} M Alunda},
  journal={Parasite immunology},
  year={2000},
  volume={22 3},
  pages={131-8}
}
A low molecular weight fraction from adult Haemonchus contortus containing two peptides (p26/23) was used to vaccinate Manchego female lambs between 3.5 and 5 months of age. Immunizing injections were given three times on days 0, 14 and 28 of the experiment. On day 43, lambs were challenged with 400 third stage larvae/kg live weight. Vaccination induced a lengthening of prepatent periods, significant reduction (> 60%) in mean faecal egg counts and smaller variations in packed cell volume values… CONTINUE READING