Vaccination models and optimal control strategies to dengue.

  title={Vaccination models and optimal control strategies to dengue.},
  author={Helena Sofia Rodrigues and M. Teresa T. Monteiro and Delfim F. M. Torres},
  journal={Mathematical biosciences},
As the development of a dengue vaccine is ongoing, we simulate an hypothetical vaccine as an extra protection to the population. In a first phase, the vaccination process is studied as a new compartment in the model, and different ways of distributing the vaccines investigated: pediatric and random mass vaccines, with distinct levels of efficacy and durability. In a second step, the vaccination is seen as a control variable in the epidemiological process. In both cases, epidemic and endemic… CONTINUE READING
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