Vaccination in humans generates broad T cell cytokine responses.


In recent years, the quantification of T cell responses to pathogens or immunogens has become a common tool in the evaluation of disease pathogenesis or vaccine immunogenicity. Such measurements are usually limited to enumerating IFN-gamma-producing cells after ex vivo stimulation with Ag, but little is known about the phenotype or complete functional… (More)


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@article{Rosa2004VaccinationIH, title={Vaccination in humans generates broad T cell cytokine responses.}, author={Stephen C. De Rosa and Fabien X Lu and Joanne L. Yu and Stephen P. Perfetto and Judith Falloon and Susan E. Moser and Thomas G. Evans and Richard A. Koup and Christopher J. Miller and Mario Roederer}, journal={Journal of immunology}, year={2004}, volume={173 9}, pages={5372-80} }