Vaccination elicits correlated immune and clinical responses in glioblastoma multiforme patients.

Abstract

Cancer vaccine trials have failed to yield robust immune-correlated clinical improvements as observed in animal models, fueling controversy over the utility of human cancer vaccines. Therapeutic vaccination represents an intriguing additional therapy for glioblastoma multiforme (GBM; grade 4 glioma), which has a dismal prognosis and treatment response, but… (More)
DOI: 10.1158/0008-5472.CAN-07-5973

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