Vaccination and herd immunity: what more do we know?

@article{Rashid2012VaccinationAH,
  title={Vaccination and herd immunity: what more do we know?},
  author={Harunor Rashid and Gulam Khandaker and Robert Booy},
  journal={Current Opinion in Infectious Diseases},
  year={2012},
  volume={25},
  pages={243–249}
}
Purpose of review This review summarizes herd immunity, focusing on conceptual developments with application to vaccination programs. Recent findings The conventional idea of herd immunity is based on the relationship between the transmission dynamics of infectious agents and population immunity. However, there have been some recent conceptual developments in vaccine ‘herd immunity’ or ‘herd protection’ that address the complexities of imperfect immunity, heterogeneous populations, nonrandom… 

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References

SHOWING 1-10 OF 64 REFERENCES

Vaccine herd effect

The herd effect has had a major impact in the eradication of smallpox, has reduced transmission of pertussis, and protects against influenza and pneumococcal disease.

Meningococcal vaccines and herd immunity: lessons learned from serogroup C conjugate vaccination programs

The magnitude of the herd effects following MCC vaccination was largely unanticipated, and has important consequences for the design and evaluation of new meningococcal vaccines.

Herd protection against influenza.

  • W. P. Glezen
  • Medicine
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
  • 2006

Herd immunity: recent uses in vaccine assessment

Human communities defend themselves against specific infectious agents in a way that extends beyond the simple sum of the immune status of its individuals. By analogy with individual immunity to

Estimation of measles vaccine efficacy and critical vaccination coverage in a highly vaccinated population

Analysis of a large outbreak in a German public school to show how estimates of key epidemiological parameters such as the basic reproduction number (R0), vaccine efficacy (VES) and critical vaccination coverage (pc) can be obtained from partially observed outbreaks in highly vaccinated populations.

Acellular Pertussis Vaccine Safety and Efficacy in Children, Adolescents and Adults

DTaP vaccination appears to establish herd immunity after sufficient uptake within communities and countries, and the economic impact of pertussis and transmission from adults to vulnerable infants provides a cost-benefit justification for widespread use of DTaP vaccines in all age groups with routine boosting every 10 years.

Updated Postlicensure Surveillance of the Meningococcal C Conjugate Vaccine in England and Wales: Effectiveness, Validation of Serological Correlates of Protection, and Modeling Predictions of the Duration of Herd Immunity

Modeling suggested that protection against carriage persists for at least 3 years and predicted the stabilization of serogroup C disease at low levels (fewer than 50 cases per year) up to 2015-2016.

Direct and indirect effectiveness of influenza vaccination delivered to children at school preceding an epidemic caused by 3 new influenza virus variants.

LAIV delivered to elementary-school children before an epidemic caused by 3 new variant influenza viruses generated significant cross-protection for the recipients and indirect (herd) protection for the community.

Rotavirus vaccines: viral shedding and risk of transmission.

  • E. Anderson
  • Medicine, Biology
    The Lancet. Infectious diseases
  • 2008
...