Vaccination and autoimmune disease: what is the evidence?

@article{Wraith2003VaccinationAA,
  title={Vaccination and autoimmune disease: what is the evidence?},
  author={David Cameron Wraith and Michel Goldman and Ph. Lambert},
  journal={The Lancet},
  year={2003},
  volume={362},
  pages={1659-1666}
}
As many as one in 20 people in Europe and North America have some form of autoimmune disease. These diseases arise in genetically predisposed individuals but require an environmental trigger. Of the many potential environmental factors, infections are the most likely cause. Microbial antigens can induce cross-reactive immune responses against self-antigens, whereas infections can non-specifically enhance their presentation to the immune system. The immune system uses fail-safe mechanisms to… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 3 times. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 88 CITATIONS

FILTER CITATIONS BY YEAR

2004
2018

CITATION STATISTICS

  • 5 Highly Influenced Citations

  • Averaged 5 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 66 REFERENCES

The effect of infections on susceptibility to autoimmune and allergic diseases

  • D Nemazee
  • N Engl J Med
  • 2002

A virusinduced molecular mimicry model of multiple sclerosis

  • L Fugger
  • J Clin Invest
  • 2001

Analysis of the relationship between viral infection and autoimmune disease

  • B Hemmer, M Jacobsen, N Sommer
  • Immunity
  • 2001

CD 4 + CD 25 + suppressor T cells

  • M Itoh, T Takahashi, N Sakaguchi
  • J Exp Med
  • 2001

Similar Papers

Loading similar papers…