Vaccination and autoimmune disease: what is the evidence?

@article{Wraith2003VaccinationAA,
  title={Vaccination and autoimmune disease: what is the evidence?},
  author={David Cameron Wraith and Michel Goldman and P. -H. Lambert},
  journal={The Lancet},
  year={2003},
  volume={362},
  pages={1659-1666}
}
As many as one in 20 people in Europe and North America have some form of autoimmune disease. These diseases arise in genetically predisposed individuals but require an environmental trigger. Of the many potential environmental factors, infections are the most likely cause. Microbial antigens can induce cross-reactive immune responses against self-antigens, whereas infections can non-specifically enhance their presentation to the immune system. The immune system uses fail-safe mechanisms to… CONTINUE READING

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