Vaccination against highly pathogenic avian influenza H5N1 virus in zoos using an adjuvanted inactivated H5N2 vaccine.

@article{Philippa2007VaccinationAH,
  title={Vaccination against highly pathogenic avian influenza H5N1 virus in zoos using an adjuvanted inactivated H5N2 vaccine.},
  author={Joost D.W. Philippa and Chantal Baas and Walter E. P Beyer and Theo M. Bestebroer and Ron A M Fouchier and Derek J. Smith and Willem Schaftenaar and Ab D Osterhaus},
  journal={Vaccine},
  year={2007},
  volume={25 19},
  pages={3800-8}
}
Highly pathogenic avian influenza (HPAI) H5N1 virus infections have recently caused unprecedented morbidity and mortality in a wide range of avian species. European Commission directive 2005/744/EC allowed vaccination in zoos under strict conditions, while reducing confinement measures. Vaccination with a commercial H5N2 vaccine with vaccine doses adapted to mean body weight per species was safe, and proved immunogenic throughout the range of species tested, with some variations between and… CONTINUE READING
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