Vaccine for hypertension: modulating the renin-angiotensin system.
- Medicine, BiologyInternational journal of cardiology
Angiotensin vaccination: What is the prospect of success?
- Medicine, BiologyCurrent hypertension reports
Angiotensin vaccination is being revisited as a strategy for treating hypertension, in the hope that new conjugates of angiotens in I and angiotENSin II will produce antibodies of sufficient titer and affinity to reduce blood pressure in patients with hypertension.
Vaccines in Development to Prevent and Treat Atherosclerotic Disease
- BiologyCardiology in review
A nicotine vaccine, an antiangiotensin vaccine, and an anti-obesity vaccine may play a therapeutic role in modifying known risk factors for the development of atherosclerosis and its complications.
Review: Update on Newer Antihypertensive Medicines and Interventions
- Medicine, BiologyJournal of cardiovascular pharmacology and therapeutics
A number of new pharmacologic targets and interventions as well as a novel method of drug delivery to patients are reviewed, which will help to facilitate attainment of optimal blood pressure levels.
Comparison of immunogenic efficacy of mono and polyvalent rabies vaccines in dogs
The monovalent vaccines were found to generate higher RVNA titers than the polyvalent vaccine, and gender of dogs did not affect vaccine efficacy except that gender had some effect on RVNA Titers generated by polyvalents vaccinated dogs.
Long-term humoral immunogenicity, safety and protective efficacy of inactivated vaccine against reindeer rabies
- BiologyFrontiers in Microbiology
The data do not support the benefit of an adjuvanted vaccine for the prevention of rabies in reindeer and the efficient rabies vaccine injection dose is determined as equal to 3 ml.
Vaccines for Hypertension and Atherosclerosis
- Medicine, Biology
The development of vaccines for hypertension and atherosclerosis may be an important strategy for the prevention and treatment of these diseases.
[Renin-angiotensin-aldosterone system (RAAS) and its pharmacologic modulation].
- Biology, MedicineActa medica portuguesa
The renin-angiotensin-aldosterone system is a neuroendocrine complex system that regulates the modulation of salt and water homeostasis, and regulation of blood pressure and regulates the vascular response to injury and inflammation.
Electrical carotid baroreceptor stimulation
- MedicineWiener Medizinische Wochenschrift
In patients with resistant hypertension, electrically activation of the baroreflex leads to an average decrease in systolic blood pressure of 38, 36, 40 and 53 mmHg at 1, 2, 3 and 4 years, respectively.
Anästhesiologisches Management bei Implantation von Barorezeptorstimulatoren
- MedicineDer Anaesthesist
Baroreceptor stimulators are novel implantable devices that activate the carotid baroreceptor reflex that results in a decrease in activity of the sympathetic nervous system and inhibition of the renin-angiotensin-aldosterone system in patients with drug-resistant hypertension.
SHOWING 1-10 OF 12 REFERENCES
Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study
- MedicineThe Lancet
A vaccine for hypertension
- BiologyJournal of hypertension
The successful production of angiotensin II antibodies in rats and humans, using a protein in which the N-terminus of the peptide is fused to a spacer sequence containing a cysteine, leading to conjugation with the surface of the highly repetitive structure of virus-like particles.
Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine (PMD3117) in hypertensive subjects.
- Medicine, BiologyClinical science
Biochemical measurements show evidence of blockade of the renin system, but higher titres will be required to achieve a decrease in blood pressure, as shown in patients with essential hypertension.
Randomized double-blind placebo-controlled study of an angiotensin immunotherapeutic vaccine ( PMD 3117 ) in hypertensive subjects
- Medicine, Biology
Biochemical measurements show evidence of blockade of the renin system, but higher titres will be required to achieve a decrease in blood pressure.
Hyperkalemia with concomitant watery diarrhea: an unusual association.
- MedicineAmerican journal of kidney diseases : the official journal of the National Kidney Foundation
Amyloid-β immunotherapy for Alzheimer's disease: the end of the beginning
- Biology, PsychologyNature Reviews Neuroscience
Immunotherapy represents one of the first tests of the amyloid hypothesis in the clinic, and is an evolving approach to the treatment of Alzheimer's disease that offers a genuine opportunity to modify disease progression.
Franz Volhard Lecture. Renin-angiotensin system: a dual tissue and hormonal system for cardiovascular control.
- Medicine, BiologyJournal of hypertension. Supplement : official journal of the International Society of Hypertension
There is increasing evidence that the local renin-angiotensin system may be involved in the maintenance of cardiovascular structure and repair, and this provides a possible mechanism for the beneficial effect of ACE inhibitors in postmyocardial infarction trials.
Growth impairment in the very preterm and cognitive and motor performance at 7 years
- Medicine, PsychologyArchives of disease in childhood
Poor postnatal growth in preterm infants, especially of the head, is associated with increased levels of motor and cognitive impairment at 7 years of age, which appears to occur largely in the postnatal rather than antenatal period and may be amenable to intervention and subsequent improvement in outcome.