Vaccination against Pseudomonas aeruginosa pneumonia in immunocompromised mice.

@article{Scarff2008VaccinationAP,
  title={Vaccination against Pseudomonas aeruginosa pneumonia in immunocompromised mice.},
  author={Jennifer M Scarff and Joanna B Goldberg},
  journal={Clinical and vaccine immunology : CVI},
  year={2008},
  volume={15 2},
  pages={367-75}
}
Immunocompromised patients are highly susceptible to infection with Pseudomonas aeruginosa. Our laboratory previously showed that intranasal administration of an attenuated Salmonella strain expressing the P. aeruginosa lipopolysaccharide O antigen was effective in clearing bacteria and preventing mortality in wild-type mice after intranasal challenge. We… CONTINUE READING