Vaccination Against Dengue: Challenges and Current Developments.

  title={Vaccination Against Dengue: Challenges and Current Developments.},
  author={Bruno Guy and Jean -Marie Lang and Melanie Saville and Nicholas A C Jackson},
  journal={Annual review of medicine},
Dengue is a growing threat worldwide, and the development of a vaccine is a public health priority. The completion of the active phase of two pivotal efficacy studies conducted in Asia and Latin America by Sanofi Pasteur has constituted an important step. Several other approaches are under development, and whichever technology is used, vaccine developers face several challenges linked to the particular nature and etiology of dengue disease. We start our review by defining questions and… CONTINUE READING
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