VWF clearance: it's glycomplicated.

VWF is a protein that is mostly known for its involvement in the hemostatic pathway, and its deficiency is associated with severe bleeding complications in a disorder known as von Willebrand disease (VWD). In the early 2000s, it was found that abnormal clearance of VWF contributes to the pathogenesis of VWD. Together with the notion that VWF regulates… CONTINUE READING