VMAT2: a dynamic regulator of brain monoaminergic neuronal function interacting with drugs of abuse.

Abstract

The monoaminergic neuron, in particular the dopaminergic neuron, is central to mediating the hedonic and addictive properties of drugs of abuse. The effects of amphetamine (AMPH) and cocaine (COC), for example, depend on the ability to increase dopamine in the synapse, by effects on either the plasma membrane transporter DAT or the vesicular transporter for… (More)
DOI: 10.1111/j.1749-6632.2010.05906.x

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