VKORC1 and CYP2C9 genotypes in Egyptian patients with warfarin resistance.

@article{Azzam2016VKORC1AC,
  title={VKORC1 and CYP2C9 genotypes in Egyptian patients with warfarin resistance.},
  author={Hanan Ahmed Galal Azzam and Hossam A Elwakeel and Ibrahim Awad and Reham M. El-farahaty and Abdel-Hady El-Gilany and Solafa A El-Sharawy},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={2016},
  volume={27 2},
  pages={121-6}
}
Warfarin is the most commonly prescribed anticoagulant drug; however, a narrow therapeutic range and a high risk of bleeding or stroke complicate its clinical use. Warfarin resistance was defined as prolonged warfarin requirements of more than 15 mg/day to achieve therapeutic anticoagulation or failure to achieve therapeutic anticoagulation with more than… CONTINUE READING