VIZ-GRAIL: visualizing functional connections across disease loci

@article{Raychaudhuri2011VIZGRAILVF,
  title={VIZ-GRAIL: visualizing functional connections across disease loci},
  author={Soumya Raychaudhuri},
  journal={Bioinformatics},
  year={2011},
  volume={27 11},
  pages={
          1589-90
        }
}
  • S. Raychaudhuri
  • Published 1 June 2011
  • Computer Science, Medicine
  • Bioinformatics
MOTIVATION As disease loci are rapidly discovered, an emerging challenge is to identify common pathways and biological functionality across loci. Such pathways might point to potential disease mechanisms. One strategy is to look for functionally related or interacting genes across genetic loci. Previously, we defined a statistical strategy, Gene Relationships Across Implicated Loci (GRAIL), to identify whether pair-wise gene relationships defined using PubMed text similarity are enriched across… Expand
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