VIP as a trophic factor in the CNS and cancer cells

@article{Moody2003VIPAA,
  title={VIP as a trophic factor in the CNS and cancer cells},
  author={Terry W. Moody and Joanna M. Hill and Robert Thomas Jensen},
  journal={Peptides},
  year={2003},
  volume={24},
  pages={163-177}
}
The effects of vasoactive intestinal peptide (VIP) on the proliferation of central nervous system (CNS) and cancer cells were investigated. VIP has important actions during CNS development. During neurogenesis, VIP stimulates the proliferation and differentiation of brain neurons. Addition of VIP to embryonic mouse spinal cord cultures increases neuronal survival and activity dependent neurotrophic factor (ADNF) secretion from astroglial cells. VIP is an integrative regulator of brain growth… CONTINUE READING
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