• Corpus ID: 14999042

VINPOCETINE : A STEP TOWARDS MEMORY ENHANCEMENT

@inproceedings{Juyal2011VINPOCETINEA,
  title={VINPOCETINE : A STEP TOWARDS MEMORY ENHANCEMENT},
  author={Vijay Juyal and Preeti Kulbe},
  year={2011}
}
Vinpocetine is a very effective tool used for memory enhancement. It is best known as cerebral vasodilator and very effective in age related memory impairment. Our memory starts decline after certain age it is basically due to damage of neurons, the drug vinpocetine has neuroprotective effect. So this drug is very effective in memory impairment. Vinpocetine dilates the blood vessels and increase the cerebral blood flow. In this review the pharmacokinetics pharmacodynemics, uses, clinical… 
Vinpocetine: Hype, Hope and Hurdles towards Neuroprotection
TLDR
Vinpocetine is a safe and non-toxic with a marvelous range of efficient and structural benefits for superior vigour and is a suitable candidate to develop various dosage forms for various disorders.
Caesalpinia sappan L. Wood is a Potential Source of Natural Phosphodiesterase-1 Inhibitors
TLDR
Cognitive impairment is a neurodegenerative disorder that disrupts memory and learning abilities and PDE1 is the most abundantly expressed in the human brain.
Current advances in transdermal delivery of drugs for Alzheimer's disease
TLDR
The technical principles, novel techniques of transdermal delivery drug, and prospects for future development for the management of cognitive and behavioral dysfunctions in AD patients are reviewed.
Evaluation of Cardioprotective Role of Vinpocetine in Isoproterenol-induced Myocardial Infarction in Rats
TLDR
Biochemical and histopathological parameters clearly indicate the cardioprotective potential of vinpocetine due to its antioxidative and myocardial membrane stabilizing effects.
Evaluation of Therapeutic Efficacy of Vinpocetine in Adjuvant Induced Arthritis Model in Rats
TLDR
Vinpocetine has potent anti-arthritic, anti-inflammatory and anti-nociceptive effects and can be used either alone or in combination with indomethacin to avoid or to decrease the serious side effects of indometHacin and to improve RA associated depression.
Nanoethosomes mediated transdermal delivery of vinpocetine for management of Alzheimer’s disease
TLDR
The results suggest that nanoethosome is an efficient carrier for transdermal delivery of vinpocetine as compared to its oral form.
DEVELOPMENT AND VALIDATION OF A UV SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF VINPOCETINE IN BULK AND TABLET DOSAGE FORM
Vinpocetine is a neuroprotective drug used in the treatment of various neurological disorders such as dementia, Parkinson’s disease, Alzheimer’s disease and other mental illnesses. The present work
Preparation and Regeneration of Protoplasts from the Ethyl Vincamine Producing Fungus CH1 (Geomyces sp.)
TLDR
This paper optimized some key factors for the preparation and regeneration of protoplasts from strain CH1, isolated and identified as a producer of ethyl vincamine, which was first obtained by endophytic fungal fermentation.
Anti-Epileptic Drug Prescription in a Psychiatric Hospital Outpatient Clinic in Southeast Nigeria
TLDR
The prescribing pattern of anti-epileptic drugs in the outpatient service of a psychiatric facility in southeast Nigeria, where carbamazepine was the most frequently prescribed drug, is described, in accordance with the treatment recommendations and needs to be encouraged.

References

SHOWING 1-10 OF 50 REFERENCES
Vinpocetine for cognitive impairment and dementia.
TLDR
The evidence for beneficial effect of vinpocetine on patients with dementia is inconclusive and does not support clinical use, and the drug seems to have few adverse effects at the doses used in the studies.
[Mechanism of action of vinpocetine].
TLDR
Evidence has been obtained that neuroprotective action vinpocetine is related to the inhibition of operation of voltage dependent neuronal Na(+)-channels, indirect inhibition of some molecular cascades initiated by the rise of intracellular Ca(2+)-levels and, to a lesser extent, inhibition of adenosine reuptake.
[Neuroprotective effects of vinpocetine in vivo and in vitro. Apovincaminic acid derivatives as potential therapeutic tools in ischemic stroke].
TLDR
Results together with former literature data indicate that apovincaminic acid derivatives possessing strong neuroprotective potential may play an important role in the therapy of ischemic stroke.
“Brain-Specific” Nutrients: A Memory Cure?
  • M. McDaniel, S. Maier, G. Einstein
  • Psychology, Biology
    Psychological science in the public interest : a journal of the American Psychological Society
  • 2002
TLDR
Experimental evaluations of several widely marketed nonprescription compounds claimed to be memory enhancers and treatments for age-related memory decline suggest that future evaluations of the possible memory benefits of these supplements might fruitfully focus on memory processes rather than on memory tests per se.
The Safety and Lack of Efficacy of Vinpocetine in Alzheimer's Disease
TLDR
It is concluded that vinpocetine is ineffective in improving cognitive deficits and does not slow the rate of decline in individuals with Alzheimer's disease.
Protective activity of ethyl apovincaminate on ischaemic anoxia of the brain.
TLDR
Effects of ethyl apovincaminate (RGH-4405, Cavinton), a new cerebral metabolic and vasodilatory agent, on cerebral regulatory functions under ischaemic anoxia were studied on immobilized cats by EEG to point to the possibility of further enhancement of cerebral regulatory processes by specific drug effects.
Ethyl apovincaminate therapy in neurovascular diseases.
TLDR
Improvement was obtained in reversible vascular diseases, such as hypertensive encephalopathy, intermittent vascular cerebral insufficiency, in the early stage or light cases of cerebral endarteriitis and cerebral arteriosclerosis, and on Cavinton effect hypoxic character of the EEG improved.
...
...