VH4-34 encoded antibodies in systemic lupus erythematosus: a specific diagnostic marker that correlates with clinical disease characteristics.

@article{Vollenhoven1999VH434EA,
  title={VH4-34 encoded antibodies in systemic lupus erythematosus: a specific diagnostic marker that correlates with clinical disease characteristics.},
  author={Ronald F van Vollenhoven and Marcia M Bieber and Matthew J Powell and Pawan Kumar Gupta and Neelima M Bhat and K L Richards and Siria Albano and Nelson N. H. Teng},
  journal={The Journal of rheumatology},
  year={1999},
  volume={26 8},
  pages={1727-33}
}
OBJECTIVE To determine the clinical significance of elevated serum levels of VH4-34 encoded antibodies (VH4-34 Ab) with respect to the diagnosis and clinical characteristics of systemic lupus erythematosus (SLE). METHODS Ninety-five patients with SLE and 344 controls were studied. The controls included 34 healthy individuals, 282 patients with nonautoimmune diseases, and 28 patients with autoimmune diseases other than SLE. VH4-34 Ab levels were measured by inhibition ELISA using anti-idiotope… CONTINUE READING