VGLUTs and Glutamate Synthesis-Focus on DRG Neurons and Pain.

@article{Malet2015VGLUTsAG,
  title={VGLUTs and Glutamate Synthesis-Focus on DRG Neurons and Pain.},
  author={Mariana Malet and Pablo Rodolfo Brumovsky},
  journal={Biomolecules},
  year={2015},
  volume={5 4},
  pages={
          3416-37
        }
}
The amino acid glutamate is the principal excitatory transmitter in the nervous system, including in sensory neurons that convey pain sensation from the periphery to the brain. It is now well established that a family of membrane proteins, termed vesicular glutamate transporters (VGLUTs), serve a critical function in these neurons: they incorporate glutamate into synaptic vesicles. VGLUTs have a central role both under normal neurotransmission and pathological conditions, such as neuropathic or… CONTINUE READING
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