VEGF-targeted magnetic nanoparticles for MRI visualization of brain tumor.

@article{Abakumov2015VEGFtargetedMN,
  title={VEGF-targeted magnetic nanoparticles for MRI visualization of brain tumor.},
  author={Maxim A. Abakumov and Natalia V. Nukolova and Marina Sokolsky-Papkov and S. N. Shein and T. O. Sandalova and Hemant M. Vishwasrao and Nadezhda F. Grinenko and Iliya L. Gubsky and Artem M. Abakumov and Alexander V. Kabanov and Vladimir P. Chekhonin},
  journal={Nanomedicine : nanotechnology, biology, and medicine},
  year={2015},
  volume={11 4},
  pages={
          825-33
        }
}
UNLABELLED This work is focused on synthesis and characterization of targeted magnetic nanoparticles as magnetic resonance imaging (МRI) agents for in vivo visualization of gliomas. Ferric oxide (Fe3O4) cores were synthesized by thermal decomposition and coated with bovine serum albumin (BSA) to form nanoparticles with Deff of 53±9nm. The BSA was further cross-linked to improve colloidal stability. Monoclonal antibodies against vascular endothelial growth factor (mAbVEGF) were covalently… CONTINUE READING

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