VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells.

@article{Eum2004VEGFRP,
  title={VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells.},
  author={Sung Yong Eum and Yong Woo Lee and Bernhard Hennig and Michal Toborek},
  journal={Experimental cell research},
  year={2004},
  volume={296 2},
  pages={231-44}
}
Polychlorinated biphenyl (PCB) congeners, a group of worldwide, persistent environmental contaminants, are known to cause carcinogenesis and tumor promotion, and may also affect the development of cancer metastasis. Because vascular endothelial cells create a selective barrier to the passage of cancer cells, we hypothesize that specific PCB congeners can disrupt endothelial integrity and increase the transendothelial migration of tumor cells. To examine this hypothesis, we elucidated the… CONTINUE READING

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cancer cellIs abnormal cell of diseaseNon-Small Cell Lung Carcinoma
VEGF regulates PCB 104-mediated stimulation of permeability and transmigration of breast cancer cells in human microvascular endothelial cells . Polychlorinated biphenyl ( PCB ) congeners , a group of worldwide , persistent environmental contaminants , are known to cause carcinogenesis and tumor promotion , and may also affect the development of cancer metastasis .
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