VEGF polymorphisms in early cervical cancer susceptibility, angiogenesis, and survival.

@article{Kim2010VEGFPI,
  title={VEGF polymorphisms in early cervical cancer susceptibility, angiogenesis, and survival.},
  author={Yun Hwan Kim and Min A Kim and In-ae Park and Woong-Yang Park and Jae Weon Kim and Seung Cheol Kim and Noh-Hyun Park and Yong Sang Song and S Kang},
  journal={Gynecologic oncology},
  year={2010},
  volume={119 2},
  pages={232-6}
}
OBJECTIVE Vascular endothelial growth factor (VEGF) plays an important role in cervical carcinogenesis. We hypothesized that VEGF genetic polymorphisms may affect cancer susceptibility, angiogenesis, and survival in patients with early cervical cancer. METHODS Among 215 healthy subjects and 199 early cervical cancer patients who were treated with surgical resection, we specifically investigated four genetic polymorphisms within the VEGF gene (-2578C>A, -460 T>C, +405G>C, and +936C>T). VEGF… CONTINUE READING

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