VEGF blocking therapy in the treatment of cancer.

  title={VEGF blocking therapy in the treatment of cancer.},
  author={Julia L Glade-Bender and Jessica J. Kandel and Darrell J. Yamashiro},
  journal={Expert opinion on biological therapy},
  volume={3 2},
It is widely accepted that tumour growth beyond a few cubic millimetres cannot occur without the induction of a new vascular supply. Inhibiting the development of new blood vessels (antiangiogenesis) is a potential approach to cancer therapy that has attracted interest in recent years. In theory, this approach should be relatively selective for tumour cells. The endothelial cells which form new vascular networks in tumours are responding to angiogenic stimuli produced by the tumour, but are… CONTINUE READING


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