VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation

@inproceedings{Xu2011VEGFAD,
  title={VEGF attenuates development from cardiac hypertrophy to heart failure after aortic stenosis through mitochondrial mediated apoptosis and cardiomyocyte proliferation},
  author={Xiao Hu Xu and Jing Xu and Lei Xue and Hai L Cao and Xiang Liu and Yijiang Chen},
  booktitle={Journal of cardiothoracic surgery},
  year={2011}
}
BACKGROUND Aortic stenosis (AS) affects 3 percent of persons older than 65 years and leads to greater morbidity and mortality than other cardiac valve diseases. Surgery with aortic valve replacement (AVR) for severe symptomatic AS is currently the only treatment option. Unfortunately, in patients with poor ventricular function, the mortality and long-term outcome is unsatisfied, and only a minority of these patients could bear surgery. Our previous studies demonstrated that vascular endothelial… CONTINUE READING

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