VEGF-activated miR-144 regulates autophagic survival of prostate cancer cells against Cisplatin

Abstract

Cisplatin is a commonly used chemotherapy drug for prostate cancer (PC). However, some PCs are resistant to cisplatin treatment, while the molecular mechanisms underlying the resistance of PCs to cisplatin are not completely understood. In this study, we found that cisplatin dose-dependently activated Beclin-1 in two PC cell lines, PC3 and LNCap. Autophagy… (More)
DOI: 10.1007/s13277-015-4383-1

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