VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses.

@article{Rissanen2003VEGFDIT,
  title={VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses.},
  author={Tuomas T Rissanen and Johanna E. Markkanen and Marcin Gruchala and Tommi Heikura and Antti Puranen and Mikko I. Kettunen and Ivana Kholov{\'a} and Risto A. Kauppinen and Marc G. Achen and Steven A Stacker and Kari Alitalo and Seppo Yl{\"a}-Herttuala},
  journal={Circulation research},
  year={2003},
  volume={92 10},
  pages={
          1098-106
        }
}
Optimal angiogenic and lymphangiogenic gene therapy requires knowledge of the best growth factors for each purpose. We studied the therapeutic potential of human vascular endothelial growth factor (VEGF) family members VEGF-A, VEGF-B, VEGF-C, and VEGF-D as well as a VEGFR-3-specific mutant (VEGF-C156S) using adenoviral gene transfer in rabbit hindlimb skeletal muscle. The significance of proteolytic processing of VEGF-D was explored using adenoviruses encoding either full-length or mature… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 195 CITATIONS

FILTER CITATIONS BY YEAR

2003
2018

CITATION STATISTICS

  • 18 Highly Influenced Citations

  • Averaged 11 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 38 REFERENCES

Similar Papers

Loading similar papers…