VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection

@article{Storkebaum2004VEGFOR,
  title={VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection},
  author={Erik Storkebaum and Diether Lambrechts and Peter Carmeliet},
  journal={BioEssays},
  year={2004},
  volume={26}
}
Both blood vessels and nerves are guided to their target. Vascular endothelial growth factor (VEGF)A is a key signal in the induction of vessel growth (a process termed angiogenesis). Though initial studies, now a decade ago, indicated that VEGF is an endothelial cell‐specific factor, more recent findings revealed that VEGF also has direct effects on neural cells. Genetic studies showed that mice with reduced VEGF levels develop adult‐onset motor neuron degeneration, reminiscent of the human… 

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TLDR
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