VE-cadherin expression allows identification of a new class of hematopoietic stem cells within human embryonic liver.

@article{Oberlin2010VEcadherinEA,
  title={VE-cadherin expression allows identification of a new class of hematopoietic stem cells within human embryonic liver.},
  author={Estelle Oberlin and Maud Fleury and Denis Clay and Laurence Petit-Cocault and J J Candelier and Beno{\^i}t Mennesson and Thierry Jaffredo and Mich{\`e}le Souyri},
  journal={Blood},
  year={2010},
  volume={116 22},
  pages={4444-55}
}
Edification of the human hematopoietic system during development is characterized by the production of waves of hematopoietic cells separated in time, formed in distinct embryonic sites (ie, yolk sac, truncal arteries including the aorta, and placenta). The embryonic liver is a major hematopoietic organ wherein hematopoietic stem cells (HSCs) expand, and the future, adult-type, hematopoietic cell hierarchy becomes established. We report herein the identification of a new, transient, and rare… CONTINUE READING