VDR microRNA expression and epigenetic silencing of vitamin D signaling in melanoma cells.

@article{Essa2010VDRME,
  title={VDR microRNA expression and epigenetic silencing of vitamin D signaling in melanoma cells.},
  author={Salma Essa and Nicole Denzer and Ulrich Mahlknecht and R{\"u}diger Klein and E. M. Collnot and Wolfgang Tilgen and Joerg Reichrath},
  journal={The Journal of steroid biochemistry and molecular biology},
  year={2010},
  volume={121 1-2},
  pages={110-3}
}
Malignant melanoma cells express the vitamin D receptor (VDR). However, some melanoma cell lines fail to respond to the antiproliferative effects of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). We reported previously that out of seven melanoma cell lines analyzed, three cell lines (MeWo, SK-Mel28, SM) respond to the antiproliferative effects of 1,25(OH)2D3… CONTINUE READING