VDR-mediated gene expression patterns in resting human coronary artery smooth muscle cells.

@article{WuWong2007VDRmediatedGE,
  title={VDR-mediated gene expression patterns in resting human coronary artery smooth muscle cells.},
  author={Jinshyun Ruth Wu-Wong and Masaki Nakane and Junli Ma and Xiaoan Ruan and Paul E. Kroeger},
  journal={Journal of cellular biochemistry},
  year={2007},
  volume={100 6},
  pages={1395-405}
}
Vitamin D analogs such as paricalcitol and calcitriol that activate the vitamin D receptor (VDR) provide survival benefit for Stage 5 chronic kidney disease (CKD) patients, possibly associated with a decrease in cardiovascular (CV)-related incidents. Phenotypic changes of smooth muscle cells play an important role in CV disease. The role of vitamin D analogs in modulating gene expression in smooth muscle cells is still not well understood. In this study, DNA microarray analysis of approximately… CONTINUE READING
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