VDAC Channels

@article{BlachlyDyson2001VDACC,
  title={VDAC Channels},
  author={Elizabeth Blachly‐Dyson and Michael Forte},
  journal={IUBMB Life},
  year={2001},
  volume={52}
}
Trafficking of metabolites across the outer mitochondrial membrane is believed to be mediated primarily by the pore‐forming voltage‐dependent anion channel, VDAC (also known as mitochondrial porin). An expanding body of in vitro studies have strongly suggest that the pore formed by VDAC can be regulated in a number of ways that implicate it as a site for the regulation of mitochondrial function, yet technical limitations have prevented the extension these studies to a relevant cellular context… 
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VDAC, located in the mitochondrial outer membrane, shows high selectivity for ATP over comparably sized ions and PorA/C1 from Neisseria meningitidis achieves high cationic selectivity and large.
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