Uveitogenic potential of lymphocytes sensitized to interphotoreceptor retinoid-binding protein.

@article{McAllister1987UveitogenicPO,
  title={Uveitogenic potential of lymphocytes sensitized to interphotoreceptor retinoid-binding protein.},
  author={Cathy G. McAllister and Barbara N Wiggert and Gerald J. Chader and Taku Kuwabara and Igal Gery},
  journal={Journal of immunology},
  year={1987},
  volume={138 5},
  pages={1416-20}
}
In our previous study rats immunized with bovine retinal interphotoreceptor retinoid-binding protein (IRBP) were found to develop inflammation in the eye and the pineal gland. This inflammatory disease was distinct in several aspects from experimental autoimmune uveoretinitis (EAU) induced by the retinal S-antigen (S-Ag). The current study examined the adoptive transfer of IRBP-induced EAU. We established that lymphocytes from IRBP immunized donor rats were capable of transferring EAU after in… CONTINUE READING

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