Uveitic macular edema: a stepladder treatment paradigm

@article{Preble2015UveiticME,
  title={Uveitic macular edema: a stepladder treatment paradigm},
  author={Janine M. Preble and Charles Stephen Foster},
  journal={Clinical investigation},
  year={2015},
  volume={5},
  pages={509-517}
}
The purpose of this review is to evaluate the treatment modalities that are commonly employed for the treatment of uveitis-related macular edema. Herein, the different drug classes used to treat the condition are described. In addition, the effectiveness, benefits and risks of the different routes of drug administration are discussed. Although some treatments have been evaluated in prospective clinical trials, most clinical research has been retrospective in nature. Thus, there is a need for… 
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Methods Citations
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6 Citations

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Emerging therapies in the management of macular edema: a review
TLDR
Three main causes ofacular edema are focused on: diabetic retinopathy, retinal vein occlusion, and uveitis, and several new biologic agents are under investigation in different clinical trials and could be important new therapeutic options in cases with a low response to first-line therapy.
Quantitative Analysis of Uveitis Macular Edema in Multiple Sclerosis Patients Receiving Deep Posterior Sub-Tenon Triamcinolone Acetonide Injection
TLDR
Posterior sub-Tenon injection of triamcinolone acetonide significantly improved visual acuity and decrease macular edema in patients with intermediate uveitis associated with multiple sclerosis.
Synergistic Effect of Combined Sub-Tenon Triamcinolone and Intravitreal Anti-VEGF Therapy for Uveitic Macular Edema
TLDR
Combined intravitreal anti-VEGF and STA is superior to STA alone for reduction of UME and visual restoration and did not increase risk for steroid-induced elevation of intraocular pressure over 6 months.
Healthcare costs among patients with macular oedema associated with non-infectious uveitis: a US commercial payer’s perspective
TLDR
NIU is associated with substantial clinical and economic burden, particularly when UME is present, and a trend of increasing healthcare costs with increasing vision loss was observed.
Vesicular phospholipid gels as topical ocular delivery system for treatment of anterior uveitis
DDDT_A_353251 1055..1066
  • 2022

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