Uveitic macular edema: a stepladder treatment paradigm

  title={Uveitic macular edema: a stepladder treatment paradigm},
  author={Janine M. Preble and Charles Stephen Foster},
  journal={Clinical investigation},
The purpose of this review is to evaluate the treatment modalities that are commonly employed for the treatment of uveitis-related macular edema. Herein, the different drug classes used to treat the condition are described. In addition, the effectiveness, benefits and risks of the different routes of drug administration are discussed. Although some treatments have been evaluated in prospective clinical trials, most clinical research has been retrospective in nature. Thus, there is a need for… 
Emerging therapies in the management of macular edema: a review
Three main causes ofacular edema are focused on: diabetic retinopathy, retinal vein occlusion, and uveitis, and several new biologic agents are under investigation in different clinical trials and could be important new therapeutic options in cases with a low response to first-line therapy.
Quantitative Analysis of Uveitis Macular Edema in Multiple Sclerosis Patients Receiving Deep Posterior Sub-Tenon Triamcinolone Acetonide Injection
Posterior sub-Tenon injection of triamcinolone acetonide significantly improved visual acuity and decrease macular edema in patients with intermediate uveitis associated with multiple sclerosis.
Synergistic Effect of Combined Sub-Tenon Triamcinolone and Intravitreal Anti-VEGF Therapy for Uveitic Macular Edema
Combined intravitreal anti-VEGF and STA is superior to STA alone for reduction of UME and visual restoration and did not increase risk for steroid-induced elevation of intraocular pressure over 6 months.
Healthcare costs among patients with macular oedema associated with non-infectious uveitis: a US commercial payer’s perspective
NIU is associated with substantial clinical and economic burden, particularly when UME is present, and a trend of increasing healthcare costs with increasing vision loss was observed.
DDDT_A_353251 1055..1066
  • 2022


Etiology and treatment of the inflammatory causes of cystoid macular edema
The mechanism of ocular inflammation in cystoid macular edema is discussed with a particular focus on the inflammatory causes: post-operative, uveitic, and after laser procedures.
Cystoid macular edema
The goal of this paper is to review the current status of this treatment for macular edema due to diabetic maculopathy, central retinal vein occlusion and post-cataract surgery and the results of recent multicenter clinical trials are quoted.
The Effects of Intravitreal Bevacizumab in Infectious and Noninfectious Uveitic Macular Edema
Bvacizumab was effective in the management of UME associated with both infectious and noninfectious uveitides and had no immunosuppressive effect against infectious agents.
Tocilizumab treatment for refractory uveitis-related cystoid macular edema
These data suggest that TCZ is effective for treating CME in otherwise treatment-refractory cases of uveitis.
Macular edema : a practical approach
"Macular Edema - A Practical Approach" provides the ophthalmologist with a synthesis of knowledge to diagnose, to determine etiology, and to offer the patient viable treatment options for his benefit.
Medical treatment of macular edema in patients with uveitis
CME, a vision threatening complication of uveitis, respond fairly well to medical treatment; however, the best VA is achieved after several months, while the improvement in VA did not differ markedly among the three treatment groups.