Utiliztion of the Suzuki Coupling to Enhance the Antituberculosis Activity of Aryl Oxazoles.


Potent antituberculosis aryl oxazoles can be made in an efficient three step process--formation of β-hydroxy amides with serine benzyl ester; cyclization to afford oxazolines; and then dehydration to give the corresponding oxazoles. Furthermore, incorporation of an appropriate aryl halide allows utilization of the Suzuki cross coupling reaction to access… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.