Utilizing poxviral vectored vaccines for antibody induction-progress and prospects.

@article{Draper2013UtilizingPV,
  title={Utilizing poxviral vectored vaccines for antibody induction-progress and prospects.},
  author={Simon J Draper and Matthew G. Cottingham and Sarah C Gilbert},
  journal={Vaccine},
  year={2013},
  volume={31 39},
  pages={
          4223-30
        }
}
Over the last decade, poxviral vectors emerged as a mainstay approach for the induction of T cell-mediated immunity by vaccination, and their suitability for human use has led to widespread clinical testing of candidate vectors against infectious intracellular pathogens and cancer. In contrast, poxviruses have been widely perceived in the vaccine field as a poor choice of vector for the induction of humoral immunity. However, a growing body of data, from both animal models and recent clinical… CONTINUE READING
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