Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes.

@article{Carmieli2006UtilizingES,
  title={Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes.},
  author={R. Carmieli and N. Papo and H. Zimmermann and A. Potapov and Y. Shai and D. Goldfarb},
  journal={Biophysical journal},
  year={2006},
  volume={90 2},
  pages={
          492-505
        }
}
Membrane-active peptides participate in many cellular processes, and therefore knowledge of their mode of interaction with phospholipids is essential for understanding their biological function. Here we present a new methodology based on electron spin-echo envelope modulation to probe, at a relatively high resolution, the location of membrane-bound lytic peptides and to study their effect on the water concentration profile of the membrane. As a first example, we determined the location of the N… Expand
46 Citations
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