Utilizing Chimeric Antigen Receptors to Direct Natural Killer Cell Activity

@inproceedings{Hermanson2015UtilizingCA,
  title={Utilizing Chimeric Antigen Receptors to Direct Natural Killer Cell Activity},
  author={David Lee Hermanson and Dan S Kaufman},
  booktitle={Front. Immunol.},
  year={2015}
}
Natural killer (NK) cells represent an attractive lymphocyte population for cancer immunotherapy due to their ability to lyse tumor targets without prior sensitization and without need for human leukocyte antigens-matching. Chimeric antigen receptors (CARs) are able to enhance lymphocyte targeting and activation toward diverse malignancies. CARs consist of an external recognition domain (typically a small chain variable fragment) directed at a specific tumor antigen that is linked with one or… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 14 times over the past 90 days. VIEW TWEETS
28 Citations
55 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 55 references

Similar Papers

Loading similar papers…