Utilization of lactic acid bacterial genes in Synechocystis sp. PCC 6803 in the production of lactic acid.

@article{Joseph2013UtilizationOL,
  title={Utilization of lactic acid bacterial genes in Synechocystis sp. PCC 6803 in the production of lactic acid.},
  author={Ancy Joseph and Shimpei Aikawa and Kengo Sasaki and Yota Tsuge and Fumio Matsuda and Tsutomu Tanaka and Akihiko Kondo},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2013},
  volume={77 5},
  pages={966-70}
}
Metabolic pathway engineering of cyanobacteria for the production of industrially important chemicals from atmospheric CO2 has generated interest recently. Here, we engineered Synechocystis sp. PCC 6803 to produce lactic acid using a lactate dehydrogenase (ldh) gene from various lactic acid-producing bacteria, Lactococcus lactis (ldhB and ldhX), Lactobacillus plantarum (ldhL and ldh), and Lactobacillus rhamnosus (ldhL). The lactic acid was secreted outside the cell using a transporter (lldp… CONTINUE READING
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