Utilization of extracorporeal membrane oxygenation in DCD and DBD lung transplants: a 2‐year single‐center experience

  title={Utilization of extracorporeal membrane oxygenation in DCD and DBD lung transplants: a 2‐year single‐center experience},
  author={Davorin Sef and Alessandra Verzelloni Sef and Prashant N Mohite and Ulrich Stock and Vladimir Trkulja and Binu Raj and Diana Garcia Saez and Balakrishnan Mahesh and Fabio de Robertis and Andr{\'e} Ruediger Simon},
  journal={Transplant International},
Donation after circulatory death (DCD) has the potential to expand the lung donor pool. We aimed to assess whether DCD affected the need for perioperative extracorporeal membrane oxygenation (ECMO) and perioperative outcomes in lung transplantation (LTx) as compared to donation after brain death (DBD). All consecutive LTxs performed between April 2017 and March 2019 at our tertiary center were analyzed. Donor and recipient preoperative characteristics, utilization of ECMO, and perioperative… 

Postoperative acute kidney injury and renal replacement therapy after DCD lung transplantation

It is suggested that DCD could be associated with worse early renal outcomes in a subset of LTx patients and justify further studies on the topic in order to refine further renal care pathways perioperatively.

Textbook outcome in lung transplantation: Planned venoarterial extracorporeal membrane oxygenation versus off-pump support for patients without pulmonary hypertension.

  • S. HalpernM. C. Wright M. Hartwig
  • Medicine
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
  • 2022

Midterm outcomes of venovenous extracorporeal membrane oxygenation as a bridge to lung transplantation: Comparison with nonbridged recipients

Early‐ and midterm postoperative outcomes of patients on VV‐ECMO as a BTT and the impact of preoperative VV-ECMO on posttransplant survival outcomes are analyzed.

Improving the predictability of time to death in controlled donation after circulatory death lung donors

  • S. OkaharaG. Snell B. Levvey
  • Medicine
    Transplant international : official journal of the European Society for Organ Transplantation
  • 2021
The CART model is useful to exclude DCD donor candidates with low probability of progression, and referral received early after ICU admission, with nonspontaneous ventilatory mode, deep coma and severe infra‐tentorial damage were relevant predictors.

The Year in Cardiothoracic Transplant Anesthesia: Selected Highlights From 2020 Part I - Lung Transplantation.

This special article focuses on the highlights in cardiothoracic transplantation literature in the year 2020, including the advances in preoperative assessment and optimization, donor management, recipient management, and updates on the perioperative management.

Intraoperative Circulatory Support in Lung Transplantation: Current Trend and Its Evidence

The approach of first identifying risk factors and then developing an adjusted strategy is presented as the ERSAS (early risk stratification and strategy) concept and can influence patient outcome in terms of both mortality and morbidity.



Bilateral lung transplantation on intraoperative extracorporeal membrane oxygenator: An observational study.

Medium-term outcome after lung transplantation is comparable between brain-dead and cardiac-dead donors.

Lung Transplantation with Controlled Donation after Circulatory Death Donors

  • I. InciS. Hillinger W. Weder
  • Medicine
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • 2018
Utilization of donation after circulatory death (DCD) donors has the potential to decrease donor shortage in lung transplantation (LTx) and utility of DCD donors is a safe option to overcome donor shortage.

Lung donation after circulatory determined death: a single-centre experience†

  • C. BarberoS. Messer J. Parmar
  • Medicine
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • 2019
Short- and medium-term outcomes after the DCD LTx are comparable with those achieved after transplantation from the DBD donors, despite a tendency to use DCD lungs for older recipients, and is a clinical option that can be used with favourable results to expand the lung donor pool.

Short- and Long-term Outcomes After Lung Transplantation From Circulatory-Dead Donors: A Single-Center Experience

Both short- and long-term outcomes in DCD lung recipients are comparable to that of DBD lung recipients, and DCD LTx can be considered a safe strategy that significantly increased the authors' transplant activity.

Long-term results after lung transplantation using organs from circulatory death donors: a propensity score-matched analysis†.

  • A. SabashnikovN. Patil A. Simon
  • Medicine
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • 2016
Long-term results after LTx with organs procured following DCD are in general comparable with those obtained after DBD LTx, however, patients transplanted using organs from DCD donors have a predisposition for development of BOS in the longer follow-up.

Extracorporeal membrane oxygenation following lung transplantation: indications and survival.

Lung Transplantation From Donation After Circulatory Death: United States and Single-Center Experience.

Normothermic ex vivo lung perfusion: Does the indication impact organ utilization and patient outcomes after transplantation?

Lungs from donation after circulatory death donors: an alternative source to brain-dead donors? Midterm results at a single institution.

  • B. ZychA. Popov A. Simon
  • Medicine
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • 2012
Medium-term results after lung transplantation with organs procured after circulatory death are comparable with those obtained after standard lung transplation, and DCD could be used to significantly increase the donor pool.